| Artist | Title | Week Ending | Weeks There |
| John Lennon | Imagine | 10 Jan 1981 | 4 |
| John Lennon | Woman | 7 Feb 1981 | 2 |
| Joe Dolce Music Theatre | Shaddap You Face | 21 Feb 1981 | 3 |
| Roxy Music | Jealous Guy | 14 Mar 1981 | 2 |
| Shakin’ Stevens | This Ole House | 28 Mar 1981 | 3 |
| Bucks Fizz | Making Your Mind Up | 18 Apr 1981 | 3 |
| Adam and the Ants | Stand and Deliver | 9 May 1981 | 5 |
| Smokey Robinson | Being With You | 13 Jun 1981 | 2 |
| Michael Jackson | One Day In Your Life | 27 Jun 1981 | 2 |
| The Specials | Ghost Town | 11 Jul 1981 | 3 |
| Shakin’ Stevens | Green Door | 1 Aug 1981 | 4 |
| Aneka | Japanese Boy | 29 Aug 1981 | 1 |
| Soft Cell | Tainted Love | 5 Sep 1981 | 2 |
| Adam and the Ants | Prince Charming | 19 Sep 1981 | 4 |
| Dave Stewart & Barbara Gaskin | It’s My Party | 17 Oct 1981 | 4 |
| The Police | Every Little Thing She Does Is Magic | 14 Nov 1981 | 1 |
| Queen & David Bowie | Under Pressure | 21 Nov 1981 | 2 |
| Julio Iglesias | Begin The Beguine (Volver A Empezar) | 5 Dec 1981 | 1 |
| The Human League | Don’t You Want Me | 12 Dec 1981 | 5 |
